Article
A meiotic gene regulatory cascade driven by alternative fates for newly synthesized transcripts.
Molecular biology of the cell - 1 Jan 2011
Cremona Nicole, Potter Kristine, Wise Jo Ann
Abstract excerpt
To determine the relative importance of transcriptional regulation versus RNA processing and turnover during the transition from proliferation to meiotic differentiation in the fission yeast Schizosaccharomyces pombe, we analyzed temporal profiles and effects of RNA surveillance factor mutants on expression of 32 meiotic genes. A comparison of nascent transcription with steady-state RNA accumulation reveals that...
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