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Article

Immunotherapy targeting pathological tau prevents cognitive decline in a new tangle mouse model.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 8 Dec 2010

Boutajangout Allal, Quartermain David, Sigurdsson Einar M

Abstract excerpt

Harnessing the immune system to clear protein aggregates is emerging as a promising approach to treat various neurodegenerative diseases. In Alzheimer's disease (AD), several clinical trials are ongoing using active and passive immunotherapy targeting the amyloid-β (Aβ) peptide. Limited emphasis...

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Identifiers

PMID: 21147995
DOI: 10.1523/JNEUROSCI.4363-10.2010
PMCID: PMC3135981

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21147995-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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