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Article

Active Aβ vaccination fails to enhance amyloid clearance in a mouse model of Alzheimer's disease with Aβ42-driven pathology.

Journal of neuroimmunology - 15 Jun 2012

Nemirovsky Anna, Shapiro Jenny, Baron Rona, Kompaniets Alex, Monsonego Alon

Abstract excerpt

Aβ vaccination has been shown to induce remarkable clearance of brain amyloid plaques in mouse models of Alzheimer's disease (AD). However, the extent to which antibody-mediated Aβ clearance is affected by predominant formation of Aβ42 over Aβ40 is unclear. Here we demonstrate for the first time...

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PMID: 22498096
DOI: 10.1016/j.jneuroim.2012.03.017

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APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22498096-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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