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Article

Advantage of high-resolution melting curve analysis over conformation-sensitive gel electrophoresis for mutational screening of BRCA1 and BRCA2 genes.

Clinica chimica acta; international journal of clinical chemistry - 18 Mar 2011

de Juan Jiménez Inmaculada, Cardeñosa Eva Esteban, Suela Sarai Palanca, González Eva Barragán, Trejo Dolores Salas, Lluch Oscar Fuster, Gilabert Pascual Bolufer

Abstract excerpt

BACKGROUND: Mutation screening of BRCA1 and BRCA2 (BRCAs) genes is a time-consuming and costly procedure that demands faster and cheaper alternative methods for routine diagnostics. The present study is aimed at comparing the results obtained with screening mutations methods, conformation sensiti...

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Source

Identifiers

PMID: 21147080
DOI: 10.1016/j.cca.2010.12.007

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21147080-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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