Article
A mitochondrial DNA variant at position 16189 is associated with type 2 diabetes mellitus in Asians.
Diabetologia - 1 Apr 2008
Park K S, Chan J C, Chuang L-M, Suzuki S, Araki E, Nanjo K, Ji L, Ng M, Nishi M, Furuta H, Shirotani T, Ahn B Y, Chung S S, Min H-K, Lee S W, Kim J H, Cho Y M, Lee H K
Abstract excerpt
AIMS/HYPOTHESIS: This multinational study was conducted to investigate the association between a mitochondrial DNA (mtDNA) T16189C polymorphism and type 2 diabetes in Asians. The mtDNA 16189C variant has been reported to be associated with insulin resistance and type 2 diabetes. However, a recent meta-analysis concluded that it is negatively associated with type 2 diabetes in Europids. Since the phenotype of an...
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