Article
Cholesterol homeostasis and high-density lipoprotein formation in arterial smooth muscle cells.
Trends in cardiovascular medicine - 1 Apr 2010
Allahverdian Sima, Francis Gordon A
Abstract excerpt
The balance between lipid accumulation and removal from cells in the artery wall is a key factor in atherogenesis. Smooth muscle cells (SMCs) are the main cell type in human intimal thickenings and some stages of atherosclerosis; however, cholesterol homeostasis in these cells has received little attention when compared with intimal macrophages. In addition, it has been demonstrated that SMCs may change phenotype...
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