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Article

Possible association of VISA gene polymorphisms with susceptibility to systemic lupus erythematosus in Chinese population.

Molecular biology reports - 1 Oct 2011

Liu Xiaowen, Jiao Yulian, Wen Xin, Wang Laicheng, Ma Chunyan, Gao Xuejun, Chen Zi-Jiang, Zhao Yueran

Abstract excerpt

Virus-induced signaling adapter (VISA), an important adaptor protein linking both RIG-I and MDA-5 to downstream signaling events, may mediates the activation of NF kappaB and IRFs and the induction of type I IFN. As the evidence has showed that Toll-like receptors (TLRs), I-IFN and IFN-inducible genes contribute to the pathogenesis of systemic lupus erythematosus (SLE), the aim of the current study was to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21127988
DOI: 10.1007/s11033-010-0590-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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