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Article

Insight into gene polymorphisms involved in toll-like receptor/interferon signalling pathways for systemic lupus erythematosus in South East Asia.

Journal of immunology research - 1 Jan 2014

Chai Hwa Chia, Chua Kek Heng, Lim Soo Kun, Phipps Maude Elvira

Abstract excerpt

Polymorphisms in genes involved in toll-like receptor/interferon signalling pathways have been reported previously to be associated with SLE in many populations. This study aimed to investigate the role of seven single nucleotide polymorphisms within TNFAIP3, STAT4, and IRF5, which are involved in upstream and downstream pathways of type I interferon production, in SLE in the South East Asian populations....

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Source

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Identifiers

PMID: 24741605
DOI: 10.1155/2014/529167
PMCID: PMC3987947

Genes

STAT4
TNFAIP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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