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Article

Genetic variation of VKORC1 and CYP4F2 genes related to warfarin maintenance dose in patients with myocardial infarction.

Journal of biomedicine & biotechnology - 1 Jan 2011

Kringen Marianne K, Haug Kari Bente Foss, Grimholt Runa M, Stormo Camilla, Narum Sigrid, Opdal Mimi S, Fosen Jan Toralf, Piehler Armin P, Johansen Per W, Seljeflot Ingebjørg, Berg Jens Petter, Brørs Odd

Abstract excerpt

The aim of this study was to investigate whether the VKORC1*3 (rs7294/9041 G > A), VKORC1*4 (rs17708472/6009 C > T), and CYP4F2 (rs2108622/1347 C > T) polymorphisms were associated with elevated warfarin maintenance dose requirements in patients with myocardial infarction (n = 105) from the Warfarin Aspirin Reinfarction Study (WARIS-II). We found significant associations between elevated warfarin dose...

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Share to Cytochrome P-450 Enzyme System
Share to Cytochrome P450 Family 4
Share to Mixed Function Oxygenases
Share to Myocardial Infarction
Share to Regression Analysis
Share to Statistics, Nonparametric
Share to Vitamin K Epoxide Reductases
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Source

Open in PubMed Open full text

Identifiers

PMID: 21127708
DOI: 10.1155/2011/739751
PMCID: PMC2992873

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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