Article
MicroRNAs prevent precocious gene expression and enable pattern formation during plant embryogenesis.
Genes & development - 1 Dec 2010
Nodine Michael D, Bartel David P
Abstract excerpt
Arabidopsis embryos lacking DICER-LIKE1 (DCL1), which is required for microRNA (miRNA) biogenesis, arrest early in development. To assess the functions of embryonic miRNAs, we determined the developmental and molecular consequences of DCL1 loss. We found that DCL1 is required for cell differentiation events as early as the eight-cell stage and soon thereafter for proper division of the hypophysis and subprotoderm...
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