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Article

DICER-LIKE 4 functions in trans-acting small interfering RNA biogenesis and vegetative phase change in Arabidopsis thaliana.

Proceedings of the National Academy of Sciences of the United States of America - 6 Sept 2005

Xie Zhixin, Allen Edwards, Wilken April, Carrington James C

Abstract excerpt

Arabidopsis thaliana contains four DICER-LIKE (DCL) genes with specialized functions in small RNA biogenesis for RNA interference-related processes. A mutant with defects in DCL4 was identified and analyzed for microRNA- and endogenous, small interfering RNA (siRNA)-related functions. The dcl4-2 mutant contained normal or near-normal levels of microRNAs (21 nt) and heterochromatin-associated siRNAs (24 nt). In...

Topics

Arabidopsis
Arabidopsis Proteins
Conserved Sequence
Gene Expression Profiling
Gene Expression Regulation, Plant
Models, Biological
Molecular Sequence Data
Mutation
Protein Structure, Tertiary
RNA Interference

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA, Small Interfering

Ribonuclease III

Ribonucleases

Source

Open in PubMed Open full text

Identifiers

PMID: 16129836
DOI: 10.1073/pnas.0506426102
PMCID: PMC1200315

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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