Article
MMP9 is protective against lethal inflammatory mass lesions in the mouse colon.
Disease models & mechanisms - 1 Mar 2011
Hald Andreas, Rønø Birgitte, Melander Maria C, Ding Ming, Holck Susanne, Lund Leif R
Abstract excerpt
The family of matrix metalloproteinases (MMPs) is responsible for extracellular matrix degradation during physiological and pathophysiological tissue remodeling processes such as embryogenesis, tissue repair and cancer progression. Despite these important roles of MMPs, inhibition or ablation of individual members of the MMP family in animal models have been shown to have little effect. It has been speculated...
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