Article
[Preliminary interpretation on the relationship between the phenotype of CD133+ cells and niche in transplanted human glioma in mice].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Aug 2010
Song Wu-chao, Fei Xi-feng, Dong Jun
Abstract excerpt
OBJECTIVE: CD133(+) tumor cells are regarded as cancer stem cells (CSCs), responsible for tumor initiation, development, and relevant with chemo- and radio-resistance of tumors. However, how the destiny of CD133(+) cells is regulated by their niche remains largely unknown. In this study the interpretation of the relationship between CD133(+) cells and their niche were performed through investigating the...
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