Article
Evidence for the formation of heteromultimeric potassium channels in Xenopus oocytes.
Nature - 7 Jun 1990
Isacoff E Y, Jan Y N, Jan L Y
Abstract excerpt
Potassium channels show a wide range of functional diversity. Nerve cells typically express a number of K+ channels that differ in their kinetics, single-channel conductance, pharmacology, and sensitivity to voltage and second messengers. The cloning of the Shaker gene in Drosophila, and of related genes, has revealed that the encoded K+ channel polypeptides resemble one of the four internally homologous domains...
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