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Article

Heteromerization of Kir2.x potassium channels contributes to the phenotype of Andersen's syndrome.

Proceedings of the National Academy of Sciences of the United States of America - 28 May 2002

Preisig-Müller Regina, Schlichthörl Günter, Goerge Tobias, Heinen Steffen, Brüggemann Andrea, Rajan Sindhu, Derst Christian, Veh Rüdiger W, Daut Jürgen

Abstract excerpt

Andersen's syndrome, an autosomal dominant disorder related to mutations of the potassium channel Kir2.1, is characterized by cardiac arrhythmias, periodic paralysis, and dysmorphic bone structure. The aim of our study was to find out whether heteromerization of Kir2.1 channels with wild-type Kir2.2 and Kir2.3 channels contributes to the phenotype of Andersen's syndrome. The following results show that Kir2.x...

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Identifiers

PMID: 12032359
DOI: 10.1073/pnas.102609499
PMCID: PMC124349

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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