Article
Haplotype phasing by multi-assembly of shared haplotypes: phase-dependent interactions between rare variants.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2011
Halldórsson Bjarni V, Aguiar Derek, Istrail Sorin
Abstract excerpt
In this paper we propose algorithmic strategies, Lander-Waterman-like statistical estimates, and genome-wide software for haplotype phasing by multi-assembly of shared haplotypes. Specifically, we consider four types of results which together provide a comprehensive workflow of GWAS data sets: (1) statistics of multi-assembly of shared haplotypes (2) graph theoretic algorithms for haplotype assembly based on...
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