Article
The iron-responsive, GATA-type transcription factor Cir1 influences mating in Cryptococcus neoformans.
Molecules and cells - 1 Jan 2011
Jung Won Hee, Kronstad James W
Abstract excerpt
Mating and sexual development have been associated with virulence in various fungal pathogens including Cryptococcus neoformans. This fungus is a significant pathogen of humans because it causes life-threatening cryptococcal meningitis in immunocompromised people such as AIDS patients. The virulence of C. neoformans is known to be associated with the mating type of the cells (α or a), with the α mating type being...
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