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Article

Mating-type locus of Cryptococcus neoformans: a step in the evolution of sex chromosomes.

Eukaryotic cell - 1 Oct 2002

Lengeler Klaus B, Fox Deborah S, Fraser James A, Allen Andria, Forrester Keri, Dietrich Fred S, Heitman Joseph

Abstract excerpt

The sexual development and virulence of the fungal pathogen Cryptococcus neoformans is controlled by a bipolar mating system determined by a single locus that exists in two alleles, alpha and a. The alpha and a mating-type alleles from two divergent varieties were cloned and sequenced. The C. neoformans mating-type locus is unique, spans >100 kb, and contains more than 20 genes. MAT-encoded products include...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 12455690
DOI: 10.1128/EC.1.5.704-718.2002
PMCID: PMC126754

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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