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Article

Chromosome 4q31 locus in COPD is also associated with lung cancer.

The European respiratory journal - 1 Dec 2010

Young R P, Whittington C F, Hopkins R J, Hay B A, Epton M J, Black P N, Gamble G D

Abstract excerpt

Chronic obstructive pulmonary disease (COPD) is the single greatest risk factor for lung cancer in smokers and is found in 50-90% of lung cancer cases. The link between COPD and lung cancer may stem in part from the matrix remodelling and repair processes underlying COPD, and the development of epithelial-mesenchymal transition (EMT) that underlies lung carcinogenesis. The Hedgehog-interacting protein (HHIP),...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21119205
DOI: 10.1183/09031936.00033310

Genes

HHIP
GYPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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