Article
Smoking status and gene susceptibility play important roles in the development of chronic obstructive pulmonary disease and lung function decline: A population-based prospective study.
Medicine - 1 Jun 2017
Zhao Junling, Li Miao, Chen Jinkun, Wu Xiaomei, Ning Qin, Zhao Jianping, Xu Yongjian, Xie Jungang, Yu Jun
Abstract excerpt
BACKGROUND: We conducted this study to identify the influences and synergistic effects of smoking status and polymorphisms in hedgehog interacting protein (HHIP) on chronic obstructive pulmonary disease (COPD) and lung function decline. METHODS: A cohort containing 306 COPD patients and 743 healthy subjects was recruited from 25,000 subjects. All selected subjects had chronic cough for over 2 years or a smoking...
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