Article
Association of HHIP polymorphisms with COPD and COPD-related phenotypes in a Chinese Han population.
Gene - 15 Nov 2013
Wang Bo, Zhou Haixia, Yang Jing, Xiao Jun, Liang Binmiao, Li Dengxue, Zhou Hong, Zeng Qingfei, Fang Chunju, Rao Zhengsheng, Yu He, Ou Xuemei, Feng Yulin
Abstract excerpt
The hedgehog signaling pathway plays an important role in lung morphogenesis and cellular responses to lung injury. Genome-wide association studies (GWAS) and integrative genomics approaches have demonstrated the associations between HHIP polymorphisms and chronic obstructive pulmonary disease (COPD) and in non-Asian populations. Here we investigated whether HHIP polymorphisms would also be associated with COPD...
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