Article
Requirement for Golgi-localized PI(4)P in fusion of COPII vesicles with Golgi compartments.
Molecular biology of the cell - 15 Jan 2011
Lorente-Rodríguez Andrés, Barlowe Charles
Abstract excerpt
The role of specific membrane lipids in transport between endoplasmic reticulum (ER) and Golgi compartments is poorly understood. Using cell-free assays that measure stages in ER-to-Golgi transport, we screened a variety of enzyme inhibitors, lipid-modifying enzymes, and lipid ligands to investigate requirements in yeast. The pleckstrin homology (PH) domain of human Fapp1, which binds...
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