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Advances in the Molecular Detection of ABC Transporters Involved in Multidrug Resistance in Cancer

28 Mar 2011

Abstract excerpt

ATP-Binding Cassette (ABC) transporters are important mediators of multidrug resistance (MDR) in patients with cancer. Although their role in MDR has been extensively studied in vitro, their value in predicting response to chemotherapy has yet to be fully determined. Establishing a molecular diagnostic assay dedicated to the quantitation of ABC transporter genes is therefore critical to investigate their...

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PMID: 21118086
DOI: 10.2174/138920111795163931

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