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Article

Genetic variants in telomere-maintaining genes and skin cancer risk.

Human genetics - 1 Mar 2011

Nan Hongmei, Qureshi Abrar A, Prescott Jennifer, De Vivo Immaculata, Han Jiali

Abstract excerpt

Telomere-related genes play an important role in maintaining the integrity of the telomeric structure that protects chromosome ends, and telomere dysfunction may lead to tumorigenesis. We evaluated the associations between 39 SNPs, including 38 tag-SNPs in telomere-related genes (TERT, TRF1, TRF2, TNKS2, and POT1) and one SNP (rs401681) in the TERT-CLPTM1L locus which has been identified as a susceptibility locus...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21116649
DOI: 10.1007/s00439-010-0921-5
PMCID: PMC3443196

Genes

TERT
NHS
POT1
TNKS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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