Article
Telomere length and the risk of cutaneous malignant melanoma in melanoma-prone families with and without CDKN2A mutations.
PloS one - 1 Jan 2013
Burke Laura S, Hyland Paula L, Pfeiffer Ruth M, Prescott Jennifer, Wheeler William, Mirabello Lisa, Savage Sharon A, Burdette Laurie, Yeager Meredith, Chanock Stephen, De Vivo Immaculata, Tucker Margaret A, Goldstein Alisa M, Yang Xiaohong R
Abstract excerpt
INTRODUCTION: Recent evidence suggests a link between constitutional telomere length (TL) and cancer risk. Previous studies have suggested that longer telomeres were associated with an increased risk of melanoma and larger size and number of nevi. The goal of this study was to examine whether TL modified the risk of melanoma in melanoma-prone families with and without CDKN2A germline mutations. MATERIALS AND...
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