Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Long telomere length and a TERT-CLPTM1 locus polymorphism association with melanoma risk.

European journal of cancer (Oxford, England : 1990) - 1 Dec 2014

Llorca-Cardeñosa Marta J, Peña-Chilet Maria, Mayor Matias, Gomez-Fernandez Cristina, Casado Beatriz, Martin-Gonzalez Manuel, Carretero Gregorio, Lluch Ana, Martinez-Cadenas Conrado, Ibarrola-Villava Maider, Ribas Gloria

Abstract excerpt

Telomere length has been associated with the development of cancer. Studies have shown that shorter telomere length may be related to a decreased risk of cutaneous melanoma. Furthermore, deregulation of the telomere-maintaining gene complexes, has been related to this oncogenic process. Some variants in these genes seem to be correlated with a change in telomerase expression. We examined the effect of 10 single...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Melanoma

Share to Melanoma, Cutaneous Malignant

Share to Membrane Proteins

Share to Skin Neoplasms

Share to Telomerase

Share to Telomere

Source

Identifiers

PMID: 25457634
DOI: 10.1016/j.ejca.2014.09.017

Genes

TERT
CLPTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Long telomere length and a TERT-CLPTM1 locus polymorphism association with melanoma risk.PMID 25457634Read ↗

Genetic variants in telomere-maintaining genes and skin cancer risk.Semantic proximity Read ↗

Meta-analysis combining new and existing data sets confirms that the TERT-CLPTM1L locus influences melanoma risk.Semantic proximity Read ↗

Telomere length, telomerase reverse transcriptase promoter mutations, and melanoma risk.Semantic proximity Read ↗

Telomere length and the risk of cutaneous malignant melanoma in melanoma-prone families with and without CDKN2A mutations.Semantic proximity Read ↗

Sequence variants at the TERT-CLPTM1L locus associate with many cancer types.Semantic proximity Read ↗

No association between TERT-CLPTM1L single nucleotide polymorphism rs401681 and mean telomere length or cancer risk.Semantic proximity Read ↗

On the interplay of telomeres, nevi and the risk of melanoma.Semantic proximity Read ↗

TERT Promoter Mutations and Telomerase in MelanomaSemantic proximity Read ↗

Long telomeres and cancer risk among 95 568 individuals from the general population.Semantic proximity Read ↗

The role of TERT-CLPTM1L SNPs, hTERT expression and telomere length in the pathogenesis of oral squamous cell carcinoma.Semantic proximity Read ↗

Genetic predisposition to long telomeres is associated with increased mortality after melanoma: A study of 2101 melanoma patients from hospital clinics and the general population.Semantic proximity Read ↗

Association between TERT-CLPTM1L rs401681[C] allele and NMSC cancer risk: a meta-analysis including 45,184 subjects.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.