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Article

Brother of cdo (umleitung) is cell-autonomously required for Hedgehog-mediated ventral CNS patterning in the zebrafish.

Development (Cambridge, England) - 1 Jan 2011

Bergeron Sadie A, Tyurina Oksana V, Miller Emily, Bagas Andrea, Karlstrom Rolf O

Abstract excerpt

The transmembrane protein Brother of Cdo (Boc) has been implicated in Shh-mediated commissural axon guidance, and can both positively and negatively regulate Hedgehog (Hh) target gene transcription, however, little is known about in vivo requirements for Boc during vertebrate embryogenesis. The zebrafish umleitung (uml(ty54)) mutant was identified by defects in retinotectal axon projections. Here, we show that...

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Identifiers

PMID: 21115611
DOI: 10.1242/dev.057950
PMCID: PMC2998166

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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