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Article

Interleukin 28B polymorphisms as predictor of response in hepatitis C virus genotype 2 and 3 infected patients.

World journal of gastroenterology - 21 Dec 2013

Mangia Alessandra, Mottola Leonardo, Santoro Rosanna

Abstract excerpt

Single nucleotide polymorphisms near the interleukin 28B (IL-28B) gene have been identified as strong predictors of both spontaneous or Peg-interferon (Peg-IFN) and ribavirin (RBV) induced clearance of hepatitis C virus (HCV). Several studies have shown that, in patients with genotype 1 (GT-1), rs12979860 C/C and rs8099917 T/T substitutions are associated with a more than twofold increase in sustained virological...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24379617
DOI: 10.3748/wjg.v19.i47.8924
PMCID: PMC3870545

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