A point mutation in the tyrosinase gene of BALB/c albino mouse causing the cysteine----serine substitution at position 85.

doi:10.1111/j.1432-1033.1990.tb15510.x

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Article

A point mutation in the tyrosinase gene of BALB/c albino mouse causing the cysteine----serine substitution at position 85.

European journal of biochemistry - 30 Apr 1990

Shibahara S, Okinaga S, Tomita Y, Takeda A, Yamamoto H, Sato M, Takeuchi T

Abstract excerpt

Murine albinism is characterized by complete lack of melanin pigments in skin and retina. In order to study the molecular basis of albinism, we have cloned and characterized the tyrosinase gene of BALB/c mice (c/c). Sequence analysis of this gene reveals a point mutation at nucleotide residue 387...

Topics

Albinism
Animals
Base Sequence
Catechol Oxidase
Cysteine
Exons
Gene Amplification
Gene Library
Mice
Mice, Inbred BALB C
Molecular Sequence Data
Monophenol Monooxygenase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Oligonucleotide Probes

Phenotype

Promoter Regions, Genetic

Restriction Mapping

Serine

Source

Open in PubMed

Identifiers

PMID: 2110899
DOI: 10.1111/j.1432-1033.1990.tb15510.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2110899-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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