Article
Genetic polymorphisms in Toll-like receptors among pediatric patients with renal parenchymal infections of different clinical severities.
PloS one - 1 Jan 2013
Cheng Chi-Hui, Lee Yun-Shien, Chang Chee-Jen, Lin Tzou-Yien
Abstract excerpt
BACKGROUND: Although several studies have suggested single gene defects or variations in the genes associated with host immune response could confer differences in susceptibility to urinary pathogen invasion, no studies have examined the genetic polymorphisms in various toll-like receptors (TLRs) that activate innate immune responses in pediatric renal parenchymal infections of different clinical severities,...
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