Article
Primordial germ cell proliferation is impaired in Fused Toes mutant embryos.
Developmental biology - 15 Jan 2011
Kim Bongki, Kim Youngha, Sakuma Rui, Hui Chi-Chung, Rüther Ulrich, Jorgensen Joan S
Abstract excerpt
Over the first 4 days of their life, primordial germ cells invade the endoderm, migrate into and through the developing hindgut, and traverse to the genital ridge where they cluster and ultimately inhabit the nascent gonad. Specific signal-receptor combinations between primordial germ cells and their immediate environment establish successful migration and colonization. Here we demonstrate that disruption of a...
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