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Article

A quantitatively-modeled homozygosity mapping algorithm, qHomozygosityMapping, utilizing whole genome single nucleotide polymorphism genotyping data.

BMC bioinformatics - 15 Oct 2010

Huqun, Fukuyama Shun-ichiro, Morino Hiroyuki, Miyazawa Hiroshi, Tanaka Tomoaki, Suzuki Tomoko, Kohda Masakazu, Kawakami Hideshi, Okazaki Yasushi, Seyama Kuniaki, Hagiwara Koichi

Abstract excerpt

Homozygosity mapping is a powerful procedure that is capable of detecting recessive disease-causing genes in a few patients from families with a history of inbreeding. We report here a homozygosity mapping algorithm for high-density single nucleotide polymorphism arrays that is able to (i) correct genotyping errors, (ii) search for autozygous segments genome-wide through regions with runs of homozygous SNPs,...

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Identifiers

PMID: 21106127
DOI: 10.1186/1471-2105-11-S7-S5
PMCID: PMC2957688

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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