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Article

HomozygosityMapper--an interactive approach to homozygosity mapping.

Nucleic acids research - 1 Jul 2009

Seelow Dominik, Schuelke Markus, Hildebrandt Friedhelm, Nürnberg Peter

Abstract excerpt

Homozygosity mapping is a common method for mapping recessive traits in consanguineous families. In most studies, applications for multipoint linkage analyses are applied to determine the genomic region linked to the disease. Unfortunately, these are neither suited for very large families nor for the inclusion of tens of thousands of SNPs. Even if less than 10,000 markers are employed, such an analysis may easily...

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PMID: 19465395
DOI: 10.1093/nar/gkp369
PMCID: PMC2703915

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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