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Article

Reactive Oxygen Species Are Required for Maintenance and Differentiation of Primary Lung Fibroblasts in Idiopathic Pulmonary Fibrosis

16 Nov 2010

Abstract excerpt

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal illness whose pathogenesis remains poorly understood. Recent evidence suggests oxidative stress as a key player in the establishment/progression of lung fibrosis in animal models and possibly in human IPF. The aim of the present study was to characterize the cellular phenotype of fibroblasts derived from IPF patients and identify...

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Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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PMID: 21103368
DOI: 10.1371/journal.pone.0014003

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