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Possible mode of emergence for drug-resistant leprosy is revealed by an analysis of samples from Mexico.

Japanese journal of infectious diseases - 1 Nov 2010

Matsuoka Masanori, Suzuki Yasuhiko, Garcia Iris Estrada, Fafutis-Morris Mary, Vargas-González Alberto, Carreño-Martinez Cristina, Fukushima Yukari, Nakajima Chie

Abstract excerpt

Mexico is a country with sporadic leprosy cases, and the reemergence of drug resistance is a concern. In this study, molecular analysis of Mycobacterium leprae was employed to clarify the spread of drug-resistant leprosy. Thus, drug resistance-determining regions in the folP1, rpoB, and gyrA genes, which are associated with resistance to dapsone, rifampicin, and ofloxacin, respectively, were analyzed by direct...

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PMID: 21099091

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