Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic analysis of the Shaker gene complex of Drosophila melanogaster.

Genetics - 1 Jun 1990

Ferrús A, Llamazares S, de la Pompa J L, Tanouye M A, Pongs O

Abstract excerpt

The Shaker complex (ShC) spans over 350 kb in the 16F region of the X chromosome. It can be dissected by means of aneuploids into three main sections: the maternal effect (ME), the viable (V) and the haplolethal (HL) regions. The mutational analysis of ShC shows a high density of antimorphic mutations among 12 lethal complementation groups in addition to 14 viable alleles. The complex is the structural locus of a...

Topics

Action Potentials
Alleles
Aneuploidy
Animals
Blotting, Southern
Crosses, Genetic
Drosophila melanogaster
Female
Heterozygote
Male
Mosaicism
Multigene Family

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Phenotype

Potassium Channels

Source

Open in PubMed Open full text

Identifiers

PMID: 2116353
DOI: 10.1093/genetics/125.2.383
PMCID: PMC1204027

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2116353-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic analysis of the Shaker gene complex of Drosophila melanogaster.PMID 2116353Read ↗

Functional relationships between genes of the Shaker gene complex of Drosophila.Semantic proximity Read ↗

Functional interactions between the gene tetanic and the Shaker gene complex of Drosophila.Semantic proximity Read ↗

Molecular basis of altered excitability in Shaker mutants of Drosophila melanogaster.Semantic proximity Read ↗

Troponin I is encoded in the haplolethal region of the Shaker gene complex of Drosophila.Semantic proximity Read ↗

Genetic modification of potassium channels in Drosophila Shaker mutants.Semantic proximity Read ↗

A voltage-clamp analysis of gene-dosage effects of the Shaker locus on larval muscle potassium currents in Drosophila.Semantic proximity Read ↗

Potassium channels in Drosophila: historical breakthroughs, significance, and perspectives.Semantic proximity Read ↗

Genetic and physical delineation of the region of the mouse deafness mutation shaker-2.Semantic proximity Read ↗

In vivo analysis of a gain-of-function mutation in the Drosophila eag-encoded K+ channel.Semantic proximity Read ↗

Localization of a Highly Conserved Human Potassium Channel Gene (NGK2-KV4; KCNC1) to Chromosome 11p15Semantic proximity Read ↗

Functional genomic analysis of the 61D-61F region of the third chromosome of Drosophila melanogaster.Semantic proximity Read ↗

Nerve terminal excitability and neuromuscular transmission in T(X;Y)V7 and Shaker mutants of Drosophila melanogaster.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.