Article
In vivo imaging of retinal gliosis: a platform for diagnosis of PD and Screening of anti-PD compounds.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference - 1 Jan 2010
Kumar S, Ho G, Zhang Y, Zhuo L
Abstract excerpt
Parkinson's disease (PD) is the second most frequent degenerative disorder after Alzheimer's disease. It is characterized by the depletion of mesenchephalic dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc) and striatal dopamine. Oxidative stress plays a major role in the pathogenesis of Parkinson's disease where DA neurons are especially vulnerable to excessive production of the H2O2...
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