Article
Contributions of the glucocorticoid receptor polymorphism (Bcl1) and childhood abuse to risk of bulimia nervosa.
Psychiatry research - 15 May 2011
Steiger Howard, Bruce Kenneth, Gauvin Lise, Groleau Patricia, Joober Ridha, Israel Mimi, Richardson Jodie, Kin Francois Ng Yin
Abstract excerpt
This study evaluated the hypothesis that traumatic stress can increase risk of bulimia nervosa (BN) in individuals who are genetically disposed towards lower modulation of physiological stress reactions. We explored the extent to which childhood abuse (physical or sexual), variants of a main glucocorticoid receptor (GR) polymorphism (Bcl1), or their interaction, differentiated women with and without BN. Women...
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