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Article

CREB1 modulates the influence of childhood sexual abuse on adult's anger traits.

Genes, brain, and behavior - 1 Aug 2012

Hasler R, Perroud N, Baud P, Olié E, Guillaume S, Malafosse A, Courtet P

Abstract excerpt

Childhood maltreatment and genes underlie vulnerability to suicidal behaviours (SB), possibly by affecting the constitution of endophenotypes such as anger traits. The CREB protein has been implicated in antidepressant response, suicide and mood disorders in general. The aim of this study was to investigate if CREB1 gene is associated with SB and/or anger-related traits and if these associations are modulated by...

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PMID: 22574704
DOI: 10.1111/j.1601-183X.2012.00807.x

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