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Article

Dopamine-system genes, childhood abuse, and clinical manifestations in women with Bulimia-Spectrum Disorders.

Journal of psychiatric research - 1 Sept 2012

Groleau Patricia, Steiger Howard, Joober Ridha, Bruce Kenneth R, Israel Mimi, Badawi Ghislaine, Zeramdini Nadia, Sycz Lindsay

Abstract excerpt

OBJECTIVE: We explored interaction effects involving polymorphisms of targeted dopamine system genes and selected forms of childhood abuse (sexual, physical and emotional) acting upon severity of binge-eating and psychopathological symptoms in women with Bulimia-Spectrum Disorders (BSDs). METHODS: Women diagnosed with a BSD (n = 216) were assessed for childhood traumata, eating-disorder (ED) symptoms, and...

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Identifiers

PMID: 22733030
DOI: 10.1016/j.jpsychires.2012.05.018

Genes

COMT
DRD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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