Article
Interaction of the BcII glucocorticoid receptor polymorphism and childhood abuse in Bulimia Nervosa (BN): relationship to BN and to associated trait manifestations.
Journal of psychiatric research - 1 Feb 2012
Steiger Howard, Gauvin Lise, Joober Ridha, Israel Mimi, Badawi Guilaine, Groleau Patricia, Bruce Kenneth R, Yin Kin N M K Ng, Sycz Lindsay, Ouelette Anne Sophie
Abstract excerpt
We recently documented a gene-environment interaction suggesting that individuals with Bulimia Nervosa (BN) differed from normal eaters as to the combined presence of the low-function allele of the glucocorticoid receptor polymorphism, BcII, and childhood abuse. The present study examined the extent to which any such interaction effect may have been attributable to behavioral impulsivity, sensation seeking,...
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