Article
Glucocorticoid receptor gene polymorphisms in Italian patients with eating disorders and obesity.
Psychiatric genetics - 1 Dec 2010
Cellini Elena, Castellini Giovanni, Ricca Valdo, Bagnoli Silvia, Tedde Andrea, Rotella Carlo Maria, Faravelli Carlo, Sorbi Sandro, Nacmias Benedetta
Abstract excerpt
OBJECTIVE: Glucocorticoids (GCs) are involved in the control of eating behaviors, and it has been proposed that GCs and their receptors (GR) could play a significant role in the pathophysiology of eating disorders (EDs) and obesity. We studied whether genetic variants, such as N363S (rs56149945), exon 9-β (rs6198), ER22/23EK (rs6189-6190), and the intronic BclI restriction site (rs41423247) polymorphisms in the...
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