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Article

Cellular senescence: putting the paradoxes in perspective.

Current opinion in genetics & development - 1 Feb 2011

Campisi Judith

Abstract excerpt

Cellular senescence arrests the proliferation of potential cancer cells, and so is a potent tumor suppressive mechanism, akin to apoptosis. Or is it? Why did cells evolve an anti-cancer mechanism that arrests, rather than kills, would-be tumor cells? Recent discoveries that senescent cells secret...

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Identifiers

PMID: 21093253
DOI: 10.1016/j.gde.2010.10.005
PMCID: PMC3073609

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21093253-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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