[A review of cellular senescence: friend or foe of tumorigenesis?].

Abstract excerpt

Cellular senescence, like apoptosis, is now widely accepted as a potent tumor suppressor mechanism operating in normal mitotic mammalian cells. Originally, it was identified as a process that limits the replicative lifespan of primary human cells in culture because of telomere attrition and was therefore termed "replicative" senescence (RS). However, previous findings have demonstrated that a phenotype...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Apoptosis
• Share to Cellular Senescence
• Share to DNA Damage