The PurR mutation of Drosophila melanogaster confers resistance to purine and 2,6-diaminopurine by elevating adenosine deaminase activity.

doi:10.1007/BF00260477

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Article

The PurR mutation of Drosophila melanogaster confers resistance to purine and 2,6-diaminopurine by elevating adenosine deaminase activity.

Molecular & general genetics : MGG - 1 Jan 1990

Dutton F L, Chovnick A

Abstract excerpt

Media supplemented with purine (7H-imidazo[4,5-d]pyrimidine) or the purine analogue 2,6-diaminopurine (DAP) can be employed to select several classes of purine-resistant variants from mutagenized cultures of Drosophila. One class results in elevated resistance to purine and diaminopurine which is...

Topics

2-Aminopurine
Adenine
Adenosine Deaminase
Animals
Chromosome Mapping
Crosses, Genetic
Drosophila melanogaster
Female
Gene Expression Regulation, Enzymologic
Genetic Linkage
Genotype
Hot Temperature
Male
Mutation
Nucleoside Deaminases
Purines
Recombination, Genetic
Repressor Proteins

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PMID: 2109178
DOI: 10.1007/BF00260477

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2109178-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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