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Production of polyhydroxyalkanoates by Escherichia coli mutants with defected mixed acid fermentation pathways.

Applied microbiology and biotechnology - 1 Aug 2010

Jian Jia, Zhang Shao-Qin, Shi Zhen-Yu, Wang Wei, Chen Guo-Qiang, Wu Qiong

Abstract excerpt

A series of Escherichia coli BW25113 mutants with reduced mixed acid fermentation were constructed. Genes ackA-pta, poxB, ldhA, adhE, and pflB encoding acetate kinase, phosphate acetyltransferase, pyruvate oxidase, D: -lactate dehydrogenase, acetaldehyde dehydrogenase, and pyruvate formate-lyase, respectively, were deleted successively. When grown under microaerobic condition, the mutants reduced approximately...

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PMID: 20535465
DOI: 10.1007/s00253-010-2706-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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