Article
Fermentation of 10% (w/v) sugar to D: (-)-lactate by engineered Escherichia coli B.
Biotechnology letters - 1 Dec 2005
Zhou S, Yomano L P, Shanmugam K T, Ingram L O
Abstract excerpt
Derivatives of ethanologenic Escherichia coli K011 were constructed for D: (-)-lactate production by deleting genes encoding competing pathways followed by metabolic evolution, a growth-based selection for mutants with improved performance. Resulting strains, SZ132 and SZ186, contain native genes for sucrose utilization. No foreign genes are present in SZ186. Strain SZ132 also contains a chromosomally integrated...
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