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Article

Purification of reversibly oxidized proteins (PROP) reveals a redox switch controlling p38 MAP kinase activity.

PloS one - 15 Nov 2010

Templeton Dennis J, Aye Myo-Sabai, Rady Joshua, Xu Fang, Cross Janet V

Abstract excerpt

Oxidation of cysteine residues of proteins is emerging as an important means of regulation of signal transduction, particularly of protein kinase function. Tools to detect and quantify cysteine oxidation of proteins have been a limiting factor in understanding the role of cysteine oxidation in signal transduction. As an example, the p38 MAP kinase is activated by several stress-related stimuli that are often...

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Identifiers

PMID: 21085594
DOI: 10.1371/journal.pone.0015012
PMCID: PMC2981573

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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