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Article

Protein kinase A binds and activates heat shock factor 1.

PloS one - 9 Nov 2010

Murshid Ayesha, Chou Shiuh-Dih, Prince Thomas, Zhang Yue, Bharti Ajit, Calderwood Stuart K

Abstract excerpt

BACKGROUND: Many inducible transcription factors are regulated through batteries of posttranslational modifications that couple their activity to inducing stimuli. We have studied such regulation of Heat Shock Factor 1 (HSF1), a key protein in control of the heat shock response, and a participant in carcinogenisis, neurological health and aging. As the mechanisms involved in the intracellular regulation of HSF1...

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Source

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Identifiers

PMID: 21085490
DOI: 10.1371/journal.pone.0013830
PMCID: PMC2976705

Genes

HSF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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