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Acute myeloid leukemia stem cells: seek and destroy

25 Nov 2009

Abstract excerpt

Most adult patients with acute myeloid leukemia (AML) die from their disease. Relapses are frequent even after aggressive multiagent chemotherapy and allogeneic stem cell transplantation. AML is a biologically heterogeneous disease, characterized by frequent cytogenetic abnormalities and an increasing spectrum of genetic mutations and molecular aberrations. Laboratory data suggest that AML originates from a rare...

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Share to Hematopoietic Stem Cell Transplantation
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PMID: 21082958
DOI: 10.1586/ehm.09.53

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